Science and Medicine

Part of Brain That Controls Movement Impacts Overeating

“The same brain area we tested here is active when obese people see foods and when drug addicts see drug scenes.”

The same part of the brain usually thought to control movement may also cause people to overeat—especially foods that are extra tasty.

The neostriatum, located near the middle and front of the brain—the part of the brain that is damaged in patients with Parkinson’s disease and Huntington’s disease—has traditionally been thought to control only motor movements.

Yet for several years, it has been known that the neostriatum is active in brains of obese people when viewing or tasting foods and in brains of drug addicts when viewing photos of drug-taking.

Published in the journal Current Biology, a new study shows that an opium-like chemical—enkaphalin—produced naturally in the brain is a mechanism that generates intense motivation to consume pleasant rewards, says Alexandra DiFeliceantonio, a doctoral student in psychology at the University of Michigan and the study’s lead author.

When researchers gave extra morphine-like drug stimulation to the top of the neostriatum in rats, it caused the animals to eat twice the normal amount of sweet fatty foodsin this case, M&M milk chocolate candies.

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Smoking Snuffs Out ‘Good’ Cholesterol

Smoking is a major risk factor for heart disease, contributing to more than one-third of deaths from heart disease annually, according to a 2008 estimate from the Centers for Disease Control and Prevention.

A toxic compound in cigarette smoke slows the production of “good” cholesterol, new research shows.

Cigarette smoking’s association with heart disease has been known for decades, but researchers have not been certain what chemicals or molecular processes in the body form the basis of that link. The new findings concerning the effect of benzo(a)pyrene on high-density lipoprotein, or HDL, are published in the journal Life Sciences.

“Smoking-related health hazards are well-recognized, and the role of smoking in promoting premature heart disease is widely appreciated,” said Arshag D. Mooradian, senior author of the study and a professor and chair of the department of medicine at the University of Florida College of Medicine-Jacksonville. “The novelty in our study is the finding of yet another mechanism by which smoking can accelerate heart disease through reduction of the ‘good’ cholesterol that normally protects the heart.”

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Survey Says Child Inactivity is Top Health Risk

Lack of exercise is No. 1 in a top 10 list of health concerns facing kids, according to a survey of adults across the United States..

Lack of exercise is No. 1 in a top 10 list of health concerns facing kids, according to a survey of adults across the United States.

The University of Michigan C.S. Mott Children’s Hospital National Poll on Children’s Health offers its annual top 10 list, in which a nationwide sample of adults was asked to identify the top 10 biggest health concerns for kids in their communities.

For the first time, not enough exercise was rated by most adults at the top of the list (39 percent). That was followed closely by childhood obesity (38 percent), and smoking and tobacco use (34 percent).

“Childhood obesity remains a top concern, and adults know it is certainly linked to lack of exercise,” says Matthew M. Davis, director of the C.S. Mott Children’s Hospital National Poll on Children’s Health. “The strong perception that lack of exercise is a threat to children’s health may reflect effective recent public health messages from programs such as First Lady Michelle Obama’s “Let’s Move” campaign.

“But adequate exercise offers many more benefits other than weight loss or preventing obesity—such as better attention and learning in school and improved sense of well-being,” says Davis, associate professor of pediatrics and internal medicine at the University of Michigan Medical School and associate professor of public policy at the Gerald R. Ford School of Public Policy.

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