Industry News

Oral Midazolam Proves Most Effective in Pediatric Sedation

Oral Midazolam Proves Most Effective in Pediatric Sedation

23 June 2017

By kindergarten, 40% of children have been diagnosed with early tooth decay or cavities, reports...

eBooks

May 2017

The Dentist’s Guide
To Managing Employees

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April 2017

Composite Vs. Porcelain’s:
What You Need To Know

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March 2017

Digital Marketing for Dentists

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February 2017

Traumatic Dental Injuries: Emergency Assessment And Treatment

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Recent Issues

June 2017

Digital Technologies: Changing the Face of Dentistry




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May 2017

Solving Aesthetic Challenges From Trauma-Based Injuries




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Salivary Gland Gene Therapy Study Yields Positive Results

Gene therapy may be safely used to study human salivary glands, according to a new study.

Scientists at the National Institute of Dental and Craniofacial Research, which is part of the National Institute of Health, stated that the phase 1 study of gene therapy in the human salivary gland displayed positive results. The information appeared in the Proceedings of the National Academy of Sciences.

Based on the study, the transferred gene, known as Aquaporin-1 could aid people who survived head and neck cancer who have problems with chronic dry mouth.

Aquaporin-1 encodes a protein that facilitates the flow of fluid in the cells. This process is similar to the way in which the salivary glands enable more studies to be conducted in this general vicinity. Salivary glands haven’t been studied closely in the past but the location, combined with the accessibility, makes these glands well-suited for gene therapy.

Bruce Baum was the lead author of the study. He’s been interested in information like this since he treated head and neck cancer survivors in the 1980s. His ideas for gene therapy began in 1991.

Many people have overcome cancer only to deal with chronic dry mouth problems. There aren’t many solutions. That’s why these studies in the salivary glands commenced in 2008.

There were 11 people studied to compile the data. Five of these people demonstrated an increase in saliva secretion and six people had no side effects.

More research is necessary to confirm these positive results.

The Wednesday Watch

Exclusive Interview: Patient Education and GentleWave

Exclusive Interview: Patient Education and GentleWave

21 June 2017

Patients are becoming more educated, as a world of information is readily available at our...

Technique of the Week

e-Prescribing with XLDent

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Drs. David Andersen and Lora Nelson explain how easy e-Prescribing...

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Show Me the Way

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This year’s International Dental Show did not disappoint: 155,000 participants from 157 countries attended,...

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Narrow-Body  Dental Implants

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