Industry News

Oral Midazolam Proves Most Effective in Pediatric Sedation

Oral Midazolam Proves Most Effective in Pediatric Sedation

23 June 2017

By kindergarten, 40% of children have been diagnosed with early tooth decay or cavities, reports...

eBooks

May 2017

The Dentist’s Guide
To Managing Employees

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April 2017

Composite Vs. Porcelain’s:
What You Need To Know

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March 2017

Digital Marketing for Dentists

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February 2017

Traumatic Dental Injuries: Emergency Assessment And Treatment

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Recent Issues

June 2017

Digital Technologies: Changing the Face of Dentistry




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May 2017

Solving Aesthetic Challenges From Trauma-Based Injuries




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Certain Molecule is Necessary for Tooth Root Formation

The International and American Associations for Dental Research recently made a discovery that could be pivotal for tooth root formation.

The protein called ß-catenin is expressed in odontoblasts and is required for root formation. The Chonbuk National Korea School of Dentistry wrote the research paper and it appeared in the Journal of Dental Research.

The tooth root and the surrounding periodontium maintain the tooth in the jaw. The root develops after the process of morphogenesis. Prior to this study, little was known about the molecular mechanisms that control tooth root formation.

Tissue-specific inactivation of ß-catenin in developing odontoblasts results in molars that lack roots and thin incisors.

Root odontoblast was disrupted in the mutant molars, which preceeded the loss of a subset of Hertwig’s epithelial root sheath. The outer layer of Hertwig’s epithelial root sheath extended without the root, making way for the molars to eventually erupt.

These results show that there is a cell-autonomous requirement for Wnt/ß-catenin, which alerts the dental mesenchyme to start root formation.

Dentist can learn a great deal of information from the tooth phenotypes, how Wnt impacts odontoblasts and the way the root develops.

The Wednesday Watch

Exclusive Interview: Patient Education and GentleWave

Exclusive Interview: Patient Education and GentleWave

21 June 2017

Patients are becoming more educated, as a world of information is readily available at our...

Technique of the Week

e-Prescribing with XLDent

e-Prescribing with XLDent

29 March 2017

Drs. David Andersen and Lora Nelson explain how easy e-Prescribing...

Technology Today

Show Me the Way

Show Me the Way

02 May 2017

This year’s International Dental Show did not disappoint: 155,000 participants from 157 countries attended,...

Implants Today

Narrow-Body  Dental Implants

Narrow-Body Dental Implants

02 May 2017

As the multibillion-dollar market for dental implants grows, many new companies are entering the...

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