Industry News

Oral Midazolam Proves Most Effective in Pediatric Sedation

Oral Midazolam Proves Most Effective in Pediatric Sedation

23 June 2017

By kindergarten, 40% of children have been diagnosed with early tooth decay or cavities, reports...

eBooks

May 2017

The Dentist’s Guide
To Managing Employees

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April 2017

Composite Vs. Porcelain’s:
What You Need To Know

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March 2017

Digital Marketing for Dentists

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February 2017

Traumatic Dental Injuries: Emergency Assessment And Treatment

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Recent Issues

June 2017

Digital Technologies: Changing the Face of Dentistry




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May 2017

Solving Aesthetic Challenges From Trauma-Based Injuries




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Using Some Immune System Cells may Successfully Treat Gum Disease

Utilizing the correct combination of immune system cells with inflamed tissues may be able to curb the red, swollen and painful gums that stem from periodontal disease.

The information comes from a new animal study from researchers at the University of Pittsburgh and appears in the online edition of the Proceedings of the National Academy of Sciences. Periodontal disease impacts 78 million Americans.

The current treatment of periodontal disease calls for daily brushing and flossing, in addition to regular dental visits. That way, oral bacteria, which cause periodontal disease, are kept in check.

But periodontal disease truly stems from an overreaction of the immune system to the presence of oral bacteria.

When the mouth is healthy, essentially it doesn’t overreact to the presence of oral bacteria.

To do the testing for this study, the research team put together a system of polymer microspheres with the goal being to release a chemokine, a signaling protein, called CCL22. This protein attracts regulatory T-cells and puts a small amount of the paste-like agent between the gums and teeth of animals with periodontal disease. The amount of bacteria didn’t indicate any change but there was a positive change in the standard measures of periodontal disease. There was decreased pocket depth and gum bleeding, indicating a reduction in inflammation because of more regulatory T-cells.

This practice has been going on for years, as there is evidence from ancient Egypt that some mummified remains show signs of teeth scraping to get rid of plaque—only now the procedures are more advanced. It’s conceivable that this finding may limit or even end the damaging effects of periodontal disease.

The Wednesday Watch

Exclusive Interview: Patient Education and GentleWave

Exclusive Interview: Patient Education and GentleWave

21 June 2017

Patients are becoming more educated, as a world of information is readily available at our...

Technique of the Week

e-Prescribing with XLDent

e-Prescribing with XLDent

29 March 2017

Drs. David Andersen and Lora Nelson explain how easy e-Prescribing...

Technology Today

Show Me the Way

Show Me the Way

02 May 2017

This year’s International Dental Show did not disappoint: 155,000 participants from 157 countries attended,...

Implants Today

Narrow-Body  Dental Implants

Narrow-Body Dental Implants

02 May 2017

As the multibillion-dollar market for dental implants grows, many new companies are entering the...

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